The ultimate goal of treatment being to try and mimic the production of insulin as closely as possible, with the minimum number of injections and monitoring (Shah et al., 2016; Roze et al., 2021), especially considering studies showing high rates of hypoglycaemia in patients with diabetes requiring insulin (Heller et al., 2020; Pinés Corrales et al., 2021). This evidence concerns the gene INS and diabetes mellitus.