TRPA1 and Pruritus: In addition, coadministration of another TRPA1 blocker, HC030031 (50 and 100 μg) dose-dependently inhibited ZnCl2- and Zn(CH3COO)2-induced itch in mice [For ZnCl2: F(2,15) = 17.49, P = 0.0001; For Zn(CH3COO)2: F(2,15) = 69.57 P < 0.0001; Figures 3E,F].