Diagnosis of postpartum AHA was confirmed by doing mixing studies for aPTT which was not corrected by adding normal plasma which confirm the presence with of inhibitor, absence of antibodies for antiphospholipid altogether with a reduced level of factor VIII, and presence of FVIII antibodies in our case confirm the final diagnosis of postpartum AHA (Table 4). This evidence concerns the gene F8 and autoimmune hemolytic anemia.