Recent findings indeed demonstrate that CCL4, and its receptor CCR5, play diverse roles in the inflammatory events underlying cardiovascular diseases and is upregulated in atherosclerosis and myocardial infarction, enhancing adhesion molecule expression and accelerating the vascular inflammation response.[52] Moreover, our study also showed a decrease in expression of the chemokine CXCL4. Here, CCR5 is linked to atherosclerosis.