NFKB1 and Hyperglycemia: A case-control study confirmed the strong association (r = 0.86) between MAGE and 8-iso-PGF2α urinary excretion rates (75), while another showed that transient hyperglycemia can induce lasting epigenetic changes in the promotor region of NFκB (a proinflammatory gene) in vitro and in mice (73).