In those 84 patients with baseline Hematotox score ≥ 2 exposed at day 30, incidence at day 30 of grade 3-4 neutropenia, grade 3-4 anemia, and grade 3-4 thrombocytopenia was 23 (21.6%), 6 (5.7%) and 23 (21.6%) respectively, with no difference between the G-CSF groups (p = 0.09, p = 0.16, p = 0.57). The gene discussed is CSF3; the disease is anemia (phenotype).