ERBB2 and neoplasm: In another report, Gao et al. promoted the potency, and duration of anti-tumor functions of HER2-redirected T cells employing an oncolytic virus (OV) that generated cytokine IL-12, checkpoint blockade, and a bispecific tumor-targeted T cell engager (BiTE) molecule, specific for CD44 variant 6 (CD44v6) [146].