A number of genes are correlated to the primary pathology of PD, encompassing α-synuclein, GBA, Parkin, and PINK1. Autosomal recessive PD is connected to the taking place of mutations in PINK1 and Parkin, which motivate damage in the degradation of injured mitochondria through activation of mitophagy [54]. This evidence concerns the gene PRKN and Parkinson disease.