PTEN and glioblastoma: Cytopathic effect(CPE) including rounding, vacuolation and syncytia formation was observed in T98G glioblastoma cells infected with rNDV-PTEN Position “1” (MOI 1), rNDV-PTEN Position “2” (MOI 1), rNDV (MOI 1), and no CPE at not infected glioblastoma cells (negative control) (Fig. 4B).