In 20% (1/5) of patients, non-metastatic disease was documented by PSMA-PET/CT imaging and the patients received curative RT treatment (20 × 3 Gy prostate RT), one oligometastatic patient was treated by hypofractionated prostate RT 60/3 Gy and bone metastasis 50/2.5 Gy and SBRT 3X9 Gy bone metastasis. The gene discussed is FOLH1; the disease is bone metastasis.