Among these, SPDL1 expression had a positive correlation with HRD in 19 cancer types (ACC, BLCA, BRCA, ESCA, GBM, KICH, KIRC, KIRP, LGG, LIHC, LUAD, LUSC, MESO, PAAD, PRAD, SARC, STAD, THCA, UCEC) (Fig. 4E), and a negative correlation with HRD in CESC and THYM (Fig. 4E). Here, SPDL1 is linked to cancer.