CTLA4 and tuberculosis: The antimicrobial peptides LL-37 and granulysin were reduced in TB lesions from human lung22,23 and lymph nodes,21 whereas Th2 (IL-4, IL-13, and CCL4) and Treg (FoxP3, CTLA-4, glucocorticoid-induced tumor necrosis factor receptor–related protein, and transforming growth factor-β) responses were enhanced together with excess expression of suppressors of cytokine signaling (SOCS-1 and -3).21