Neoplasm with clear cells features, Although CD10 positivity raises concern for metastatic renal cell carcinoma, the fact that the neoplastic cells are negative for RCC and PAX8 makes this possibility less likely although not entirely ruled out. CD10, is also a myoepithelial marker and together with focal positivity for p63 and calponin raises the possibility of a primary salivary gland neoplasm of epithelial‐myoepithelial origin. The gene discussed is MME; the disease is tumor of salivary gland.