These results did not change with the exclusion of the 6 cases with a juvenile onset: anytime cancer occurred in 6 LB NXP2+ with an adult onset (6/53, 11.3% vs 40/190, 21.2%; p = 0.11), and CAM in 3 adults NXP2+ (3/53, 5.7% vs 20/190, 10.5%; p = 0.42). Here, MORC3 is linked to cancer.