PTK2B and breast cancer: To define the influence of PYK2 on breast cancer growth, we established a syngeneic breast cancer model by orthotopic implantation of wild‐type (WT) and PYK2 knockout (KO) breast cancer (BC) cells into WT or PYK2ko/ko (PYK2 KO) C57BL/6 mice (Figure 1A,B),[25, 26] respectively.