M2‐like macrophages express specific cellular markers, including ARG1, YM1, FIZZ1, and the cell–surface scavenger receptors MRC1/CD206 and CD163.[6, 10, 11] These cells support tumor progression and metastasis through several mechanisms, including secretion of numerous growth factors, cytokines, and ECM‐remodeling molecules and metalloproteinases that promote tumor growth, migration, and angiogenesis.[12]. This evidence concerns the gene ARG1 and neoplasm.