Interestingly, LncMEG3 inhibits autophagy in lung cancer chemotherapy while inducing autophagy in nasopharyngeal carcinoma cells,33, 34 and the E2F1‐P53 regulatory axis suppresses replicative stress in differentiating cells and prevents tumorigenesis,35 establishing a potential effect of LncMEG3/E2F1/autophagy in regulating AML. The gene discussed is E2F1; the disease is lung cancer.