To confirm whether YFP+ naïve‐like CD4+ T cells remained committed to producing IFN‐γ in the TH17‐polarizing disease setting of the T‐cell transfer colitis model, we co‐transferred naïve‐like CD45.2+ YFP+ CD4+ T cells and naïve CD45.1+ CD4+ T cells (at a ratio of 1:9 within a total of 2,50,000 cells) into Rag2–/– mice. The gene discussed is CD4; the disease is colitis.