Several CircRNAs, including CiR-SRY [22], hsa_Circ_0001649 [23], Circ_0005230 [24], CircRNA Cdr1as [25], Circ-SMARCA5 [26], and Circ-CCAC1 [27] have been found to regulate the progression of CCA and serve as potential biomarkers for CCA. Here, SMARCA5 is linked to cholangiocarcinoma.