INS and Insulin resistance: Curcumin has shown beneficial effects on glycemic parameters (fasting plasma glucose (FPG), 2-h postprandial (2hpp), HbA1C, insulin, insulin sensitivity (IS) and insulin resistance (IR)) in prediabetic patients [11], lipid profiles (TG, TC, LDL-C, and HDL-C) and blood pressure (BP) in T2DM [8] and metabolic syndrome [6].