Trajectory groups with obesity were more likely to be had higher proportion of older individuals, history of disease (hypertension, diabetes, and hyperlipidemia), and tea drinker, longer seat time, higher level of salt intake, lower high-density lipoprotein cholesterol (HDL-C), and higher blood pressure, waist circumference (WC), hip circumference (HC), triglycerides (TG), total cholesterol (TC), fasting blood glucose (FBG), CRP, and low-density lipoprotein cholesterol (LDL-C), compared with other trajectory groups. The gene discussed is CRP; the disease is Hypertension.