Several studies have recently reported that PD‐L1 is also detected on EVs in many cancer types, such as prostate cancer [9], melanoma [8], breast cancer [123], head and neck cancer [124], pancreatic cancer [125], glioblastoma [114], gastric cancer [126], and NSCLC [127] (Table 2). This evidence concerns the gene CD274 and familial pancreatic carcinoma.