CD274 and breast carcinoma: Similarly, a recent report demonstrated that miR-34a negatively modulates PD-L1 expression, thereby suppressing the proliferation, metastasis, and invasion of gastric tumor cells [93].Moreover, miR-200 in NSCLC [87]and breast cancer [90], miR-152 in gastric cancer [92], miR-217 in laryngeal cancer [89], miR-124-3p in colorectal cancer [91], and miR-383-5p in breast cancer [86] are thought to play a role in the inhibition of PD-L1 expression.