Afterwards, the validation study indicated that hsa_circRNA_000407, has_circRNA_006169, and has_circRNA_101213 levels were enhanced in IDH-wild type GBM tissues, while the hsa_circRNA_011883, hsa_circRNA_406155, and hsa_circRNA_101341 were silenced [102]. This evidence concerns the gene IDH2 and glioblastoma.