MCL1 and gallbladder cancer: CircPVT1 results to be involved also in gall bladder cancer (GBC) where Wang S. and colleagues demonstrated that it is upregulated and promotes proliferation, migration and invasion as well as inhibits cell apoptosis acting as a miRNA sponge for miR-339-3p thus upregulation its target MCL-1 (myeloid cell leukemia-1) which is an anti-apoptotic protein involved in cancer progression [73].