Alternatively, other studies were conducted regarding the expression of the lncPVT1 in hepatocellular carcinoma and Guo J. and colleagues showed that it results upregulated and mediates the recruitment of EZH2 in order to stabilize mdm2 (Mouse double minute 2 homolog ) protein that in turn inhibits p53 expression leading to apoptosis inhibition [113]. Here, TP53 is linked to hepatocellular carcinoma.