MeRIP-seq and proteomics analysis indicated that YTHDF1, an m6A reader, recruited initiation factors and facilitated ribosome loading to promote ATG2A and ATG14 translation through recognition of the m6A site at their CDS, thus mediating autophagy under hypoxia and HCC malignancy [113]. Here, YTHDF1 is linked to hepatocellular carcinoma.