For instance, Faecalibacterium prauznitsii plays an important role in maintaining intestinal homeostasis by production of short-chain fatty acids (SCFAs) from dietary fibers.7 This species has been described as reduced in IBS patients and, in addition to exert anti-inflammatory properties,8 is able to reduce CHS in murine model of IBS.9 The gene discussed is LYST; the disease is irritable bowel syndrome.