Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy affecting 1 in 3500 newborn boys and is caused by one of the thousands of identified mutations in DMD gene (1) encoding dystrophin, a scaffolding protein that supports muscle structure by anchoring the cytoskeleton with the sarcolemma. The gene discussed is DMD; the disease is Duchenne muscular dystrophy.