Several studies, that examined OC-positive endothelial progenitor cells (EPCs) or performed histological staining for OC, reported that higher OC levels were associated with an increase of markers of atherosclerosis and calcification [28, 29], possibly indicating that these OC-positive EPCs are a promising biomarker for severity stratification of CAD [30]. The gene discussed is BGLAP; the disease is coronary artery disorder.