About 1 month later, her BNP level and liver dysfunction were improved (BNP, 32.6 pg/mL; aspartate aminotransferase, 26 U/L; alanine transaminase, 24 U/L; alkaline phosphatase, 256 U/L; γ-glutamyl transpeptidase, 14 U/L; lactate dehydrogenase, 138 U/L). The gene discussed is NPPB; the disease is Decreased liver function.