RB1 and bacterial infectious disease: designed multifunctional upconversion nanoparticles (UCNP@SiO2‐RB NPs) by enclosing hematoporphyrin monomethyl ether into its yolk‐structured up‐conversion core and covalently linking the photosensitizer of RB on its silica (SiO2) shell.[118] The UCNP@SiO2‐RB NPs possessed combined photodynamic/sonodynamic ability and achieved 100% antimicrobial efficiency against antibiotic‐resistant pathogenic bacteria, showing great potential for clinical synergistic treatment of bacterial infectious diseases.[119]