Moreover, ectopic expression of mutant TP53 with hotspot mutations observed in MM and other tumors (Y126H, R175H, R282G, and E285K) in H929‐TP53WT and H929‐TP53KO cells caused slight elevation of NEK2 mRNA levels, while protein levels were increased dramatically (Figure 3K–N). This evidence concerns the gene NEK2 and Miyoshi myopathy.