It was previously reported that NEK2 can be regulated by E2F1, E2F3, and E2F4 and that these genes are targets of p53.[19] By using GEP data (GSE2658) mining, we found that the expression of E2F8, but not other E2Fs, positively and strongly correlates with NEK2 expression in MM samples (r = 0.79, Figure 6D, Figure S6F, Supporting Information). This evidence concerns the gene E2F1 and Miyoshi myopathy.