Previous findingsevidence that individuals without cognitive decline carryingAPOE ε4 variant (related to the accumulation of amyloidbeta (Aβ)) demonstrated an increased decline in the verbalepisodic memory and hippocampal hypotrophy in the presenceof KIBRA rs17070145 СС-genotype compared to minorT-allele carriers (Porter et al., 2018). The gene discussed is WWC1; the disease is Mental deterioration.