Moreover, KEGG pathway analysis suggested that HSF2 was associated with signaling pathways related to the spliceosome, RNA transport, cell cycle, ubiquitin-mediated proteolysis, and Hippo signaling pathway in BRCA; spliceosome, cell cycle, MAPK signaling pathway, mRNA surveillance pathway, and shigellosis in CESC; spliceosome, cell cycle, viral carcinogenesis, oocyte meiosis, and RNA transport in LUAD; and RNA transport, ubiquitin-mediated proteolysis, hepatitis B infection, pathogenic Escherichia coli infection, and Salmonella infection in STAD (Figures 6A–D). This evidence concerns the gene HSF2 and escherichia coli infection.