Univariate Cox regression analysis demonstrated that HSF2 expression (p < 0.001), T stage (p < 0.001), N stage (p < 0.001), M stage (p < 0.001), and TNM stage (p < 0.001) were significantly correlated with OS in KIPR (Figure 4A); HSF2 expression (p < 0.05), T stage (p < 0.001), M stage (p < 0.001), and TNM stage (p < 0.001) were obviously correlated with OS in ACC (Figure 4D); HSF2 expression (p < 0.001), M stage (p < 0.05) and TNM stage (p < 0.001) were strongly correlated with OS in LIHC (Supplementary Figure S5A). This evidence concerns the gene HSF2 and adrenal cortex carcinoma.