CD8A and neoplasm: In line with the previous results, MIT-high group had higher inflammatory infiltration but tumor-promoting immune environment (e.g., CD8+ T, CD4+ T cells, Tregs, Th2 and M2 macrophages), while MIT-low group exhibited higher stroma infiltrations (e.g., CAFs, Endothelial and Pericytes) (Figures 4D,E).