METTL3 stabilized the expressions of HK2 (HGNC:4923) and SLC2A1 (HGNC:11005) in CRC through a m6A-IGF2BP2/3-dependent mechanism to regulate glycolytic pathways and promote colorectal cancer progression (Shen et al., 2020). The gene discussed is IGF2BP2; the disease is colorectal cancer.