Among the 17 RBPs, FXR1/2, FMR1, PUM2 (HGNC:14958), LIN28A (HGNC:15986), IGF2BP2/3, HNRNPH1 (HGNC:5041), and SRSF1 were closely related to mRNA m6A methylation in CRC. Here, IGF2BP2 is linked to colorectal carcinoma.