PFKFB2 and neoplasm: LncRNA LINC00092 interactes with 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2) to sustain the CAFs-like features of fibroblasts within tumor microenvironment and promote ovarian cancer metastasis (Zhao et al., 2017).