PALB2 and non-small cell lung carcinoma: A total of 5,227 patients with NSCLC from two centers (the First Affiliated Hospital of Guangzhou Medical University and MaoMing People`s Hospital) were analyzed using NGS; the baseline characteristics of the patients are shown in Table 1; 3.1% (162/5227) harbored germline PALB2 mutation (PALB2gmut) and 1.66% (87/5227) harbored somatic PALB2 mutation (PALB2smut).