In the GEPEIA database, shown in Figures 2A, B, high expression of PLAU in LGG was associated with a shorter OS(p=2.2e-5) and DFS(p=0.0076), whereas no difference was found between high and low expression of PLAU in OS and DFS(p=0.19, p=0.15 respectively) (Figures 2C, D) in GBM. Here, PLAU is linked to glioblastoma.