After combining the synonyms and analogous keywords, the 10 most prominent keywords with the highest frequency were GPX4 (73 times), iron (73 times), RO (46 times), NRF2 (44 times), ferroptosis-related signature (27 times), cell death (26 times), ferroptotic cell death (25 times), erastin-induced ferroptosis (23 times), lung adenocarcinoma (22 times), and cancer cell (22 times). This evidence concerns the gene GPX4 and lung adenocarcinoma.