ERBB2 and breast cancer: These cell lines represent HER2+, luminal B and luminal A breast cancer, respectively.9 Patients with each subtype present with distinct histological characteristics and clinical outcomes.9,69 Interestingly, S100A7 was overexpressed in two of the cell lines while S100P was upregulated in all three cell lines upon flow stimulation (Fig. 3d), suggesting a potential role during breast cancer progression.