IGHE and allergic rhinitis: In addition, the researchers also found that the topical application of two outer shells (A 20 and 40 mL), 5 days a week, from day 21 to 41 with BALB/c mice with allergic rhinitis, reduces the allergic effects, eosinophil penetration of nasal turbinine mucosa and OVA-specific IgE volumes, five days a week, from day 21 to day 41.