TPD52L2 and gastric cancer: In this study, the TPD52L2 role was evaluated in gastric cancer cells (OXA-resistant) through the construction of siRNAs to knockdown the expression level of TPD52L2 in cells, i.e., SGC-7901-OXA and MGC-803-OXA, and it was investigated that TPD52L2 silencing leads to the significant decrease in the proliferative and colony-forming capacity of cells.