Macrophage chemotaxis towards MM BM niche and shift to the tumorigenic M2 phenotype is mediated via CCL2, CCL3, CCL14, CXCL12, CSF-1, GM-CSF, MSP, PDGF, and TGF−β,which are produced by MM-associated MSCs (109). Here, TGFB1 is linked to Miyoshi myopathy.