Upregulated FKBP4 was found significantly related to luminal A, luminal B, HER2-positive and basal-like subtype of BC patients than the normal group (Figure 1A), and downregulated NRF2 was significantly related to luminal A, luminal B, HER2-positive and basal-like subtype patients than the normal group (Figure 1B), and the same results for TISIDB database (Figure S2). This evidence concerns the gene ERBB2 and breast cancer.