In addition to the mitochondria, MAVS has also been found on peroxisomes, where it can induce a unique signaling pathway that specifically triggers IFNλ expression but not IFNβ in response to certain viral infections (Dixit et al., 2010; Odendall et al., 2014; Bender et al., 2015). This evidence concerns the gene IFNB1 and viral infectious disease.