The C57BL/6 mice incubated with SFTSV (HB29 strain, 105 TCID50) by intramuscular (i.m.)route developed some characteristic abnormalities of SFTS in a short period of time post-infection (p.i.), having onset of leukocytopenia at day 1 p.i. and thrombocytopenia at day 3 p.i., showing an increase of ALT, AST and BUN, and shedding SFTSV via various excreta. This evidence concerns the gene GPT and Thrombocytopenia.