IL6 and rheumatoid arthritis: There are also many studies showing that IL-6 plays a key role in the pathogenesis of many immune diseases and chronic diseases, such as rheumatoid arthritis (28), idiopathic arthritis (29), diabetes (30), asthma, etc. After the treatment of rheumatoid arthritis and asthma with blocking IL-6, inflammatory activity was significantly suppressed (31, 32).