ESR1 and breast carcinoma: In colocalization analyses for RHOD (using summary data from the GTEx platform) the posterior probability of colocalization (i.e. exposure and outcome are associated and share the same causal variant) was 84% for overall breast cancer risk and 98% for ER+ breast cancer risk suggesting that breast cancer risk and RHOD expression are both associated and share a single causal variant (Table 3).