CXCL12 and Miyoshi myopathy: As illustrated in Fig. 1a, the homing of MM cells from peripheral blood to BM is known to be driven by the chemoattract CXCL12 (10 kDa) expressed by BM cells, including mesenchymal stem cells (MSCs), BM stromal cells (BMSCs), and osteoblasts (OSBs)16.