PIK3C2A and Hypercholesterolemia: The most common TEAEs (≥10%) were vomiting (34%), nausea (32%), hypercholesterolemia (31%), aspartate aminotransferase (AST) elevated (31%), alanine aminotransferase (ALT) elevated (30%), hypertriglyceridemia (24%), hypertension (22%), creatine phosphokinase (CPK) elevated (20%), diarrhea (14%), hyperlipidemia (14%), rash (13%), dizziness (11%), γ-glutamyl transpeptidase (γ-GGT) elevated (11%), and upper respiratory infection (11%) (Table 2).