However, similar to the observations with FLIP(L), sensitivity to MEDI3039 did not significantly correlate with MCL-1 (MCL1) mRNA expression in colorectal cancer, although significant correlations between low MCL-1 mRNA expression and sensitivity to MEDI3039 were observed in DLBCL and bladder cancer (Supplementary Fig. S3E). Here, MCL1 is linked to diffuse large B-cell lymphoma.